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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4004fa22ef26fb5ae2114aa34e9320f521a46c2412b8948bcf48d13e0be19668' 
  AND token = 'jWhkTtyY3MIwBjzTbGwkQA4Ky7bOTG9jD0B0CPYE8ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}