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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c437c6b0d0b17a8aa66c97882f6427d3b53decf4f3d6f5d42a03f58501749d7' 
  AND token = 'XaEzmcbBkq5IYXVEmHN6wD+y9QxvNrD5r6SrQg7z4JQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}