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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea5645deaf0c35af2ca05f68fde05f5db448e9a76c38c1f142fc2b2a562198d' 
  AND token = 'pbMykCU1MDMET4UDjpJ3I7aQ5FH1DFVCcvoXQ7ZHgBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}