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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06211f2ca3021ae37d646209525dd0def4f583495025fd80368e7aa25d3fa2d3' 
  AND token = 'orSVL66MHu7REh07+BrGQrodc04mbkH0LxOx5Ha/zx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}