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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd3af94549fcf0cb41cd47f6631d4333280d2e3e186e44655eb85e91798be9cc' 
  AND token = 'PJlsjkkAKf8RjW04Sv0QC/0+oaeLPZRNTSHaFgP7oVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}