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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d44f0cfb57a6a09d4fe19614eb8e297d9aae284d5f863aca43b9590bec1b530' 
  AND token = 'npZU0cet/Wqs7EGElO7zhzz9TqMF4qdgGB3f4s/pSyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}