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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0df6248aef50a0b3d4771ab822b40017dd627ad4a188543e78fd063d7552600f' 
  AND token = 'IMKBQj3i0oHVvDY+sUnd5gtBlBbj2zvHsFMEmAd+d+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}