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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c5efa510b7ba79c6bd7cbd0496bbe7e80a13a1e35c2367275ce33336cfc007' 
  AND token = 'GJ5k7QEnMVk4p6dStg9vP3/QuNhboSWJGBBkEB3f1BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}