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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6275694c7f212f3cb371991cd9f2141d0b29f84ce42c8488c83525b64b91539' 
  AND token = 'b1EoUrSZALYkND/OY2QsXTBq9XitQcwG8pPWR7+f/uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}