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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1005cb8ea3bd407e35cbcc7537c2af28332b361979caafd01805a64f8516cd38' 
  AND token = 'o08/7nYe11cdvsl+Y7YlRUisUXCuuVUEB6nJbwOFRzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}