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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbfe015b298b4498aca3e5b74878056fe3a9e69d0a0f9918981c2bc5b3d64495' 
  AND token = 'q2BMK7qpd3TY9/PFyKus8sbDZuPBau49Ro0OvBi9VjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}