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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a00a8f1fdebe45045818dbed11833c9450cf25bf5bde623b26410d2857d19f6' 
  AND token = '8H61gWywi1BYqOrnvmSV3I/K0BcK/VjERNQL9M8iyxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}