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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492393b7ab8dac8233fd3a0397823eaeac9b72465b2d07a0b10c077ead1c670b' 
  AND token = 'SN2KOMKF+knZfEPy507QCrp0ZRXsUv3p7jfQ4nWOaqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}