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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2d8e85192f7a821cf847989f06c9cb30ce1c61a23680cbddbe3c8022759717' 
  AND token = 'l9l6dPk1MpJoKIgxu0XBPwE+Z4nk6rpFxq3jKU1FG4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}