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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5569e38af4633c198d4a48399112997d687658245a8f78697956df91aafc847d' 
  AND token = 'KXPlL95XdLiTyzjSmCc5+kNDhKXQoCSVYexfj5ItIfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}