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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043f3e0ebf4955a5d45c9c4d1851edb4671bdb13e8d2d783ad627c17ced623bb' 
  AND token = 'WKPpFbea6uR5d457p5hKEBsz5j7mfUnfRfZE35kVEto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}