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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ca38be4e32ced0abc89ddc385de9ba95ef7692ff789483c211bdca5e053423' 
  AND token = 'tabekMCWIHnpaOW+/k2O/+02XCrQiLcrWBjnJJwivkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}