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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb745bd0ef9d129923c1b2c6faf48797e32f53e2e14033232c1eb1bc4b834757' 
  AND token = 'VLe0+OoKYbERXPoSTU1tU6NPLGG7nkVBakV5Yl10Llo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}