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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46aa52c425c018cfc04b2c63721bfe1b1c733dd412797ab0c7dffbdf4e8a0cc0' 
  AND token = 'uj1BCg++5cs0esuzk/izV6uLeSLq8+7jm1MHxYBeYtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}