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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd362978569d459e664d8a5f4932d33fa2dc92d18aaa321a6473268a0ce88c4ed' 
  AND token = 'W2EAXZGW7tjZaq+LFLfc2+Y6KURKw+QE3VfbngS7Sgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}