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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78193d3b0b458bba292225a012630cd7cfa54a29d499691808da217b74182c55' 
  AND token = 'DioC+XdTKjDeTw5q7ftTrczkoNUt6WdFD9GT/5Ksz94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}