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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac6f35d2febfef4a2e766e4d68d3fbd5f2c7440f4f6014efc56ebe5859987314' 
  AND token = 'YjTRbpHa6hC1jNWFNnPCKu6QMES9zh3TxRw/OxW+idM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}