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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f2dfd643f5e60060e88734976aae74f53a85aa4b71e43e7df748a80799c5101' 
  AND token = 'kIRO/I/C/egT3B0QMJZ0j5AXUGMt0FLI8cmeBA82Dc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}