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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd946a5754384c8e72a06ab0b906f3125b90bddb2d713dc2a00e71cdda67ebc75' 
  AND token = 'wo2dez5e8ezrNvbnAmyOV656qEt+TtdurUX/IXHG2cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}