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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a909e487a8fe71e68e8f17b3e5b40ab4bc97e01735c9e27483e093d953dc223f' 
  AND token = '7ysjS15k5H+Ec/VBDGB0z2KD8fpHeXpp+MeHWL6b00I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}