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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9f069b707ba4c9152c7d16fabd65152dd1cf7a918655b89fd70d9b4d6b0b81' 
  AND token = 'Te5NrQFT6wsTfVWfed5q8YAwKLQUXHh42eVQ5zP7cB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}