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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722317c3c8ac70e5d5a4d43391ee3620cbda7485253226dc2f6d4dcc2107d52c' 
  AND token = 'vHZy01WEfUXbpckinvttlii8HMKV1X2SictVHy6H3KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}