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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5307e85a9a493bab1cb04bb89732910d26f0b2ac6cacf9b240b65523cc45a622' 
  AND token = 'n/CNuTkBoeNsItrdu8znd2bmMJf/t7uTHH27lGiWf8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}