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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '997cb13f664b596878c096cede69f4f93772944183a6d92d7568e08faa455eba' 
  AND token = 'IJ5T4T5J9BpV8C/+sLJA4I7ypOXSLeSgENXzZBkwiTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}