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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bbc17786a9027d333a79a9d1b74e7c2488c8f78755a8fd55f926930fc8a187c' 
  AND token = '/0xqGg8QvrsoteoynPnVyQL7yCKKlpFE6X/4cZqCp/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}