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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5671a39bace4eb4c6a6ce5672d4c042a3cadc28e2bb938569288ca75a9dad6c' 
  AND token = 'YA65/sEMtkeQMmYO97I49p1GrmovhKG4IAbJu+SLTzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}