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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e4cfcd1f8c6c2de0dc0bfda7b6b582c5278ff57ecf632a4bb5bec7f71dec18' 
  AND token = 'IW/v/IvxV10QD5Ki1m2R+5XL/A89GDz5ZXcBVTN7k3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}