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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9f7f55262086686cb7a18d5857b2e16cf3750bfca9386295b3804efeda07da' 
  AND token = 'Ex7iluNXqWsF1xdDUW3ihI+uCEV+5NZAch0aGpTiqcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}