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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0d748077c0045dbf3f4f098e90a433757ea2f8149c36cd4bc2734f4e0da8137' 
  AND token = 'IRZGzXvr9fItb6/LVnpxAhnVr7L1beGix3OyruAtyZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}