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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc44acefbc661970fb3852950e8ae45adaf4e97daf12b69ec34a98f783a2590' 
  AND token = 'I2s2ham5PTYDB8ZBS4mqKcgBt0kr4GQiQp19pN4JVpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}