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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '878fe3c7623fc19e1f6bd141c4c78bc042cc7100f43e68877da85188bef771df' 
  AND token = '4RYnGK62nZyw/8srbAmuJ7BY4JEDszG5ZODxx6+WkTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}