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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f2b7aa2fde05111a2024a42d097376e2284e243fffdb0b53a93348033f60129' 
  AND token = 'nV54Nv0HxGgGJnnNRuCWyQrK+lM7aeipN1P70nD57YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}