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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f48474a19f5172003a4091d5b890d80afd0ba3e99e11c20f1b086aafbdaa2b1' 
  AND token = 'F8yxy8mps+00fpS7EWirUv0KSXTlMTYHKZXUihAvYuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}