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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8f9a37ccc7862a803003a0a3da059fc6cb70ce5fa5635248352cd00d2aad718' 
  AND token = 'i+ptkAbdMAh06ZhhQ1SCTTyux9Pheybf1ivX2qkwn0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}