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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a086a90b25709386e2ec248dd5e1bedbbb58f419f21a498e4b22940ba70a7b' 
  AND token = 'gkSetHTWxvMT5H0GeCk8dtEKltPKcEx8g1LzUMfHd2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}