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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a263ee651470e4e8f4152323f75a51f06f06ad3fd877c5d48005a55b01e0a6b0' 
  AND token = 'U7ZfjKhY+nMHeCVWJ3v+chjwzzrixiLOdHdwbV223Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}