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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135c086f147be268918895220a44e31cf32d5143b45d5883b43f38ac2716491b' 
  AND token = 'cEGcoRG+JBQz2FLSdbCksdM7T9NRkhHk1qLiMk6ZOpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}