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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3288a66a5bbcc3323a8d76c725c645b9c80800910eb1a7ce98bb80e0841738ff' 
  AND token = 'zgayhRqhgji1X8KqrbzO+ut7bHpOSyXRrAQS42D5oJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}