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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57dd8cf28568cccce2ff239446d3f99278e6647bb154bf00005c24e411fd9b3f' 
  AND token = '6z5nFXvK2vF1htt0g7Br65fah0bbfKlK2si2yLSdlzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}