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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fcc73d039b1a0d66023171fd6750a4e07eb0ea07b3c4068d4afc0d1b5379b55' 
  AND token = 'nOdpROS+I7vPLxjPyG+2oMxpQ+73o7NL4Tv6KlPbJf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}