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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e92a79f900011652d681cff05e46485e9cc946481564021fd7cf9a2d7d5b770' 
  AND token = 'hpiZX4G+Sapuh9oO1hcbVDDb2chDCxN6eqv8OFFCUlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}