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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66ffee7bac2c0ba65962411cd60f629325ce6004524b57b0af390b2657d6950' 
  AND token = 'ltwe0hTNnGxAWdSmH/sRn79yHPQsxDQLgX/tG1NWVts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}