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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd821fbf4887d9a63dd8ea78a4f9806889bc21d73993092db9c20a4ee32a3aa3' 
  AND token = 'FtI9IpH35CyJb7rPSjW9aYOZTzd9VAfp1uGZCrb29cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}