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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b9fe8d977725a6217924d5eab8e8a33d7b2fb5e5bcfed0f56ac76e4e760716' 
  AND token = 'tD4qhlM2skHDIiitg8NLZzRgClnmCCCOaqNVJMSsT54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}