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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe9ca9a0c45e0e63499f88cb2265de34d89db8bd4add073faf57d956aed39f48' 
  AND token = 'Wi6bI2eZmD8zqEqZxaXPsJNM2rRWVEe/8vG8vus6nOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}